Description
Estradiol, Ultrasensitive, LC/MS - Diagnostic applications of estradiol assays include assessment of ovarian function in a wide variety of situations (menstrual disorders, precocious or delayed puberty, assisted reproduction protocols). For men, estradiol measurement may be useful in the evaluation of gynecomastia.
The Estradiol test measures the circulating levels of estradiol which is important for assessing the ovarian function and monitoring follicular development for assisted reproduction protocols. Estradiol plays an essential role throughout the human menstrual cycle. Elevated estradiol levels in females may also result from primary or secondary ovarian hyperfunction.
Estradiol is also called 17 beta-estradiol. The ovaries, breasts, and adrenal glands make estradiol. During pregnancy, the placenta also makes estradiol.
Estradiol helps with the growth and development of female sex organs, including the uterus,fallopian tubes,vagina and breasts.Estradiol helps to control the way fat is distributed in the female body. It’s also essential for bone and joint health in females.
Estradiol testing is done to look for causes of abnormal menstrual periods,abnormal vaginal bleeding and infertility in women.During and after menopause, a woman’s body will gradually produce less estrogen and estradiol, contributing to the symptoms experienced during menopause. A test of your estradiol level can help to prepare to enter menopause.Estradiol test can also indicate how well the ovaries are working
Males also have estradiol in their bodies. Their levels of estradiol are lower than the levels in females. In males, the adrenal glands and testes make estradiol. In men testosterone levels decrease while their estrogen levels increase as they age. High estrogen levels in men contribute to prostate cancer, heart disease, loss of muscle mass, fatigue, low libido, erectile dysfunction.Estradiol has been shown in vitro to prevent destruction of sperm cells, but its clinical importance in sexual function and development in men is likely less significant than in women.
Reference Range(s)
Adult
Male =29 pg/mL
Female
Follicular Stage 39-375 pg/mL
Luteal Stage 48-440 pg/mL
Postmenopausal =10 pg/mL
Pediatric Male
(pg/mL) Female
(pg/mL)
Pre-pubertal (1-9 Years) =4 =16
10-11 Years =12 =65
12-14 Years =24 =142
15-17 Years =31 =283
