Description
IgA - Increased IgA is associated with monoclonal IgA myeloma, respiratory and gastrointestinal infections, and malabsorption; decreased IgA is found in selective IgA deficiency and in ataxia telangiectasia.
Immunoglobulin A (IgA) is the antibody which plays a critical role in the immune function of mucous membranes of the sinuses, lungs, intestines and stomach. The amount of IgA produced mutually with mucosal membranes is more than all other types of antibody in total.IgA exists in two isotypes forms named IgA1 and IgA2. Both the forms are glycosylated proteins. Around 80% of IgA1 is seen in serum while percentage of IgA2 are higher in secretions than in serum.IgA1 and IgA2 secreting ratio varies in the different lymphoid tissues of the body.
IgA deficiency can be a genetic health problem.IgA deficiency will not show any symptoms of a health problem,it is usually found from blood test.
Reference Range(s)
Cord Blood 1-3 mg/dL
1-28 days 2-40 mg/dL
1-3 months 3-40 mg/dL
4-6 months 7-47 mg/dL
7-11 months 12-53 mg/dL
1 year 20-73 mg/dL
2 years 20-99 mg/dL
3-5 years 22-140 mg/dL
6-8 years 31-180 mg/dL
9-11 years 33-200 mg/dL
12-16 years 36-220 mg/dL
17-60 years 47-310 mg/dL
=61 years 70-320 mg/dL
