Description
SHBG have an important role as a transport protein for androgen and estrogen hormones. SHBG is primarily secreted in the liver even if several other tissues make small quantities. This is released to the bloodstream the primary role of sex hormone-binding globulin is to bind up testosterone and estradiol.
Testosterone, Total, Males (Adult), Immunoassay - Testosterone circulates almost entirely bound to transport proteins: Normally less than 1-2% is free. The principal transport protein for testosterone is known as sex hormone binding globulin (SHBG) or testosterone-estradiol binding globulin (TeBG).
SHBG deformity can cause symptoms such as excessive hair growth and sexual abnormalities.
Testosterone measurements are used to assess erectile dysfunction, infertility, gynecomastia, and osteoporosis and to assess hormone replacement therapy.
